Blood vessels form a migratory scaffold in the rostral migratory stream
نویسندگان
چکیده
منابع مشابه
Cell migration in the rostral migratory stream.
Adult neurogenesis in the olfactory bulb of rodents is provided by cells which migrate tangentially from their site of genesis into the forebrain subependymal layer (SEL). This migration involves 'chains' of neuroblasts sliding into a meshwork of astrocytic cells and processes (glial tubes). The analysis of this process in postnatal rodents and in adult rabbits reveals different types of relati...
متن کاملProliferation but not migration is associated with blood vessels during development of the rostral migratory stream.
Blood vessels play a critical role in regulating neural stem cell proliferation and migration. We show here that blood vessels became progressively aligned in the direction of the rostral migratory stream (RMS) from embryonic day 14 to postnatal day 4. Dividing cells revealed by phosphohistone H3+ immunoreactivity were statistically closer to isolectin B4+ blood vessels than predicted by chance...
متن کاملSpecialized vasculature in the rostral migratory stream as a neurogenic niche and scaffold for neuroblast migration.
Neurovascular niches serve as the hosts for adult neural stem cells in both the hippocampus and subventricular zone. The rostral migratory stream (RMS) vasculature has been found to be important for neuroblast migration, while its roles in hosting putative neural stem cells have not been investigated. Here we investigated the organization of RMS vasculature and its contribution to the productio...
متن کاملEGF-Induced Expansion of Migratory Cells in the Rostral Migratory Stream
The presence of neural stem cells in the adult brain is currently widely accepted and efforts are made to harness the regenerative potential of these cells. The dentate gyrus of the hippocampal formation, and the subventricular zone (SVZ) of the anterior lateral ventricles, are considered the main loci of adult neurogenesis. The rostral migratory stream (RMS) is the structure funneling SVZ prog...
متن کاملExperimental Cerebral Malaria Spreads along the Rostral Migratory Stream
It is poorly understood how progressive brain swelling in experimental cerebral malaria (ECM) evolves in space and over time, and whether mechanisms of inflammation or microvascular sequestration/obstruction dominate the underlying pathophysiology. We therefore monitored in the Plasmodium berghei ANKA-C57BL/6 murine ECM model, disease manifestation and progression clinically, assessed by the Ra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Comparative Neurology
سال: 2009
ISSN: 0021-9967,1096-9861
DOI: 10.1002/cne.22093